Microcystin-LA

Microcystin

Last updated at: Oct. 13, 2023

Recommended name
Microcystin-LA
Synonyms
n/a
Recommended acronym
MC-LA
Abbreviation

Progenitors

No progenitors registered

Vector Species

No vector species registered

Structure
Formula
n/a
Exact mono-isotopic mass
n/a
Molfile
n/a
Alternative molfiles
n/a
SMILES
Alternative SMILES
n/a
InChi key
Alternative InChi keys
n/a
InChi
Alternative InChis
Spectra available
Unknown
Chem files
Certified
Unknown
Certified links
Non certified reference material
Unknown

Chemical analysis

Research
True
Standardized
Unknown
Validated
True
Official
EPA document # EPA/600/R-17/344

Structure recognition assays

Research
Unknown
Standardized
Unknown
Validated
Unknown
Official
n/a

Functional assays

Research
Unknown
Standardized
Unknown
Validated
Unknown
Official
n/a

Animal assays

Research
Unknown
Standardized
Unknown
Validated
Unknown
Official
n/a

References

Shoemaker, J.A., Tettenhorst, D.R., de la Cruz, A., 2017
Shoemaker, J.A., Tettenhorst, D.R., de la Cruz, A., 2017. Single Laboratory Validated Method for Determination of Microcystins and Nodularin in Ambient Freshwaters by Solid Phase Extraction and Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS), U.S. Environmental Protection Agency, EPA document # EPA/600/R-17/344.
Samdal, I.A., Ballot, A., Løvberg, K.E., Miles, C.O., 2014
Samdal, I.A., Ballot, A., Løvberg, K.E., Miles, C.O., 2014, Multihapten approach leading to a sensitive ELISA withbroad cross-reactivity to microcystins and nodularin. Environ. Sci. Technol. 2014, 48, 14, 8035–8043
Wang, C.C., Petty, E.E., Smith, C.M., 2016
Wang, C.C., Petty, E.E., Smith, C.M. 2016. Rapid and efficient analysis of microcystins, nodularin, cylindrospermopsin, and anatoxin-a in drinking water by LC tandem MS, J. AOAC Int. 99, 1565-1571.
Turner, A.D., Waack, J., Edwards, C., Lawton, L, 2018
Turner, A.D., Waack, J., Lewis, A., Edwards, C., Lawton, L. 2018. Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powder. J. Chromatogr. B 1074-1075, 111-123.
Altaner, S., Puddick, J., Fessard, V., Zemskov, I., Dietrich, D.R., 2019
Altaner, S., Puddick, J., Fessard, V., Feurstein, D., Zemskov, I., Dietrich, D.R. 2019. Simultaneous Detection of 14 Microcystin Congeners from Tissue Samples Using UPLC- ESI-MS/MS and Two Dierent Deuterated Synthetic Microcystins as Internal Standards. Toxins 11, 388.
Regulatory status
Unknown

References

US EPA, 2015
United States Environmental Protection Agency, Drinking Water Health Advisory for the Cyanobacterial Microcystin Toxins. EPA-820R15100.
Human toxic syndrome(s)
n/a
Organ system toxicity
n/a
Risk assessment
Unknown
Molecular targets known
Unknown
Molecular targets
n/a
Toxic to aquatic animals
Unknown
TEF available
Unknown
Notes
Wade Huang
Contact
Zhihong Wang
Contact